Florida Highway Patrol says, as of 2:15 p.m. both the inside and middle lane have now reopened on I-10.
According to FHP, the driver of an 18-wheeler struck a guard rail and lost their load.
The wreck caused a major traffic backup on the highway. FHP says traffic remains backed up about four miles.
Crews are currently helping reload the 18-wheeler. FHP did not say what cargo the truck was hauling.
No injuries were reported.
